Anti-MAPK1 Antibody

The MAPK1 protein, also known as ERK2, sits at the core of the RAS-RAF-MEK-ERK signal transduction cascade and is studied extensively in cancer biology, where its constitutive activation drives proliferation in many tumor types.

This Rabbit Polyclonal primary antibody from Antibodies.com is raised against MAPK1 and supplied as an unconjugated IgG in a 200 µl liquid vial, giving laboratories flexibility to pair it with HRP, biotin, or fluorophore-conjugated secondary reagents. Recommended storage is at -20 °C in a frozen state to preserve activity through multiple freeze-thaw cycles.

Validated applications include Western blot for protein-level detection in cell and tissue lysates, immunohistochemistry for localization in fixed tissue sections, and flow cytometry for intracellular staining workflows performed in vitro using human samples. The polyclonal format recognizes multiple epitopes across the target, which can be advantageous when working with samples that carry sequence variation or post-translational modification states. Researchers investigating downstream phosphorylation events, pathway inhibition studies, or biomarker validation across oncology and signal transduction projects commonly select this reagent.