Anti-MAP4K5 Antibody

This rabbit polyclonal primary antibody from Antibodies.com targets MAP4K5 (Mitogen-Activated Protein Kinase Kinase Kinase 5), a serine/threonine kinase that functions upstream in stress-activated JNK signaling cascades governing cell proliferation, survival, and inflammatory responses. The reagent is supplied as 50 µl of unconjugated IgG and is validated for Western blot detection of the human, mouse, and rat orthologs across lysates from cultured mammalian lines and primary tissues. Polyclonal recognition of multiple epitopes on the kinase domain supports reproducible band detection at the expected molecular weight under standard denaturing SDS-PAGE conditions. Investigators studying TNF-driven apoptosis, TNF receptor signaling, or upstream kinase regulation in cancer and immune cell models use this reagent to probe MAP4K5 expression and its modulation by cellular stress, cytokines, and small-molecule inhibitors. The unconjugated format allows flexible pairing with HRP, fluorophore, or biotin secondary reporters chosen to match the detection platform, while the rabbit host and IgG isotype enable broad compatibility with standard western blot workflows.