Anti-MAP3K7 (Ab-187) Antibody

This phospho-specific polyclonal antibody from Antibodies.com targets MAP3K7, also known as TAK1 (TGF-β-activated kinase 1), and is raised against an epitope centered on residue 187, a threonine autophosphorylation site whose modification marks the catalytically activated form of the kinase. Supplied as 100 µL of unconjugated rabbit antiserum, the reagent is validated for Western blot and immunohistochemistry on human samples, allowing researchers to distinguish active kinase from the inactive pool in cell lysates and fixed tissue sections. Because MAP3K7 sits upstream of NF-κB and JNK/AP-1 signaling, the antibody is useful for studies of inflammatory signaling, TNF receptor responses, IL-1 pathway activation, and cellular stress. The polyclonal format provides broader epitope coverage than a monoclonal reagent, supporting consistent detection across denatured and partially denatured targets, while the unconjugated presentation permits flexible pairing with HRP-, fluorophore-, or biotin-labeled secondary antibodies to match diverse detection chemistries.