Anti-MAP3K2 Antibody

MAP3K2 (Mitogen-Activated Protein Kinase Kinase 2), also known as MEKK2, is a serine/threonine kinase that operates upstream in the MAPK signaling cascade, feeding into both JNK and ERK activation downstream of cytokine and stress cues. The Antibodies.com polyclonal reagent is raised in rabbit and supplied as an unconjugated 1 mg/ml stock in phosphate buffered saline containing 0.05% sodium azide at approximately pH 7.2, packaged as a 100 µl vial sized for routine western blot workflows. The antibody recognizes endogenous MAP3K2 across human, mouse, and rat samples, supporting signaling studies in models of inflammation, cell survival, and oncogenic contexts where MEKK2 contributes to tumor progression. Researchers probing upstream kinase activity in lysate preparations can apply the reagent at working dilutions matched to their chosen chemiluminescent or chromogenic detection system. For handling, refrigerate the vial upon receipt, protect from light, and limit freeze-thaw cycles of the stock to preserve binding activity.