Anti-MAP3K12 Antibody

This rabbit polyclonal IgG antibody targets MAP3K12 (Mitogen-Activated Protein Kinase Kinase 12), also referred to as Dual Leucine Zipper Kinase (DLK), a serine/threonine kinase that acts upstream of the JNK signaling cascade. The reagent is supplied by Antibodies.com as an unconjugated polyclonal antibody raised in rabbit, validated for Western blot detection of the human protein.

The antibody is offered at a working volume of 200 µL and is reactive with human samples. It is provided as an IgG isotype reagent in unconjugated format, allowing flexible secondary antibody selection for chemiluminescent or fluorescent Western blot workflows. MAP3K12 plays a documented role in neuronal stress signaling, axon degeneration, and JNK-mediated responses to cellular injury, supporting its use in neuroscience, cell signaling, and apoptosis research.

For Western blot applications, the antibody can be used to detect endogenous MAP3K12 in lysates prepared from human cell lines and tissues. Keep the antibody refrigerated; aliquot upon first use to limit freeze-thaw cycles and preserve reagent activity.