Anti-MAP3K11 Antibody

This unconjugated rabbit polyclonal antibody from Antibodies.com targets MAP3K11, the mixed lineage kinase 3 (MLK3) serine/threonine kinase that sits at the head of stress-activated MAPK cascades driving JNK and p38 signaling. The reagent is supplied as 100 µl of polyclonal antiserum and is validated for Western blot and immunohistochemistry workflows on human samples.

MAP3K11 acts as a JNK pathway activator implicated in neuronal stress responses, neuroinflammatory signaling, and tumor cell migration, making antibodies raised against it useful for studies of neurodegeneration, glioblastoma invasion, and TNF-alpha-induced apoptosis pathways. Researchers probing phosphorylation-dependent JNK activation in cell culture lysates or IHC of neural and tumor tissue benefit from a reagent that detects the endogenous human kinase without an attached fluorophore or enzyme tag.

For best results, store the antibody refrigerated at 2 to 8 degrees C, aliquot upon arrival to limit freeze-thaw cycles that erode polyclonal titer, and avoid prolonged exposure to light. Each lot is intended for research use only and is not validated for diagnostic or therapeutic applications.