Anti-MAP3K10 Antibody

This polyclonal antibody from Antibodies.com is raised in rabbit and specifically recognizes MAP3K10 (Mitogen-Activated Protein Kinase Kinase 10), a serine/threonine kinase also known as MLK2 that operates within the stress-activated JNK signaling cascade. The antibody has been validated for western blot and shows reactivity with human, mouse, and rat samples, supporting cross-species studies in neuronal signal transduction, stress response, and apoptosis research.

Supplied at 1 mg/ml in phosphate buffered saline (PBS, pH 7.3) with 0.05% sodium azide as a preservative, the unconjugated antibody is provided in a 100 µl volume appropriate for multiple western blot experiments. MAP3K10/MLK2 plays a documented role in neuronal development and the regulation of programmed cell death, and it has been investigated as a target in studies of neurodegenerative disease mechanisms and certain cancer cell lines where JNK pathway dysregulation is implicated.

For optimal antibody stability, aliquot upon first use and store refrigerated; avoid repeated freeze-thaw cycles. This research use only reagent enables detection of endogenous MAP3K10 in lysates derived from brain tissue, cultured neurons, and transfected cell lines.