Anti-MAP2K7 Antibody

This rabbit polyclonal antibody targets MAP2K7, also known as MKK7, a dual-specificity kinase that phosphorylates and activates JNK family kinases within the stress-activated MAPK signaling cascade. Supplied by Antibodies.com as a 100 µl unconjugated reagent, the antibody is validated for western blot, immunohistochemistry, immunofluorescence, and immunoprecipitation workflows across human, mouse, and rat samples.

MAP2K7 functions upstream of c-Jun N-terminal kinase and mediates cellular responses to inflammatory cytokines, oxidative stress, and DNA damage. Investigators in apoptosis, neurobiology, oncology, and inflammation research rely on this polyclonal reagent to probe JNK pathway activation, characterize phosphorylation-dependent signaling events, and map tissue distribution of the kinase in cultured cells and fixed tissue sections.

The unconjugated format allows flexible downstream conjugation to HRP, fluorophore, or biotin reporters selected by the end user. Rabbit host origin combined with polyclonal clonality delivers broad epitope recognition, which is useful when a single monoclonal fails to detect endogenous MAP2K7. Refrigerate the vial upon arrival, aliquot to reduce freeze-thaw cycles, and protect from light to preserve antibody activity through the stated shelf life.