Anti-MAP2K5 Antibody

Affinity-purified polyclonal reagent raised in rabbit against MAP2K5 (dual-specificity mitogen-activated protein kinase kinase 5), the upstream activator of ERK5 in the non-canonical BMK1/ERK5 signaling cascade. Antibodies.com supplies this unconjugated primary antibody at 1 mg/ml in PBS containing 0.1% sodium azide and 50% glycerol, packaged as a 100 µl vial. Validated for western blot, immunohistochemistry on frozen and paraffin-embedded sections, and immunofluorescence in human, mouse, and rat samples, the reagent supports studies of mechanotransduction, cardiac and neuronal development, and tumor cell signaling where MEK5-ERK5 activity contributes to proliferation, survival, and stress responses. Aliquot upon receipt and store at -20 degrees C for long-term use; thaw only what is needed to limit freeze-thaw cycles of the glycerol-containing stock. The unconjugated format allows pairing with HRP, fluorescent, or biotinylated secondary reagents for chemiluminescent, confocal, or chromogenic detection workflows in basic and translational research laboratories.