Anti-MAP2K2 Antibody

This rabbit polyclonal antibody targets MAP2K2 (Mitogen-Activated Protein Kinase Kinase 2), commonly known as MEK2, a dual-specificity threonine/tyrosine kinase that phosphorylates and activates ERK1/2 downstream of RAF within the canonical RAS/MAPK signaling cascade. Raised in rabbit and supplied as an unconjugated reagent, it is validated for Western blot and immunohistochemistry workflows on human, mouse, and rat samples, supporting investigations of cell proliferation, differentiation, survival signaling, and oncogenic pathway analysis. Researchers commonly deploy it to probe both phosphorylated and total MEK2 levels in cell lysates by immunoblotting, or to map MEK2 expression patterns in tissue sections by chromogenic staining. The reagent is provided by Antibodies.com in a 100 µl volume, sufficient for multiple standard blot or staining experiments, and is recommended for research use only, including studies of cardio-facio-cutaneous syndrome mechanisms and melanoma or other RAS-driven tumor models where MEK2 activity is a focus.