Anti-MAP1LC3A Antibody

Raised in rabbit as a polyclonal antiserum, this unconjugated primary antibody targets MAP1LC3A, a well-characterized autophagy marker used to monitor autophagosome biogenesis and flux across a broad spectrum of cell biology and disease models. Supplied as 100 µl of ready-to-use reagent, the antibody is validated for western blot, immunohistochemistry, and immunofluorescence workflows on human, mouse, and rat samples. Investigators working on neurodegeneration, cancer, metabolic stress, and programmed cell death pathways routinely track the conversion of cytosolic LC3A-I to the lipidated LC3A-II form as a readout of autophagosome accumulation. The polyclonal format from Antibodies.com offers broader epitope coverage than many monoclonal alternatives, supporting consistent detection of LC3A processing during autophagy induction or inhibition studies. For long-term use, the reagent is stored refrigerated and protected from light, with aliquots recommended to limit repeated freeze-thaw cycles of the antibody stock.