Anti-MAP1B Antibody

MAP1B (Microtubule-Associated Protein 1B) is a neuronal cytoskeletal regulator essential for microtubule stability, axon outgrowth, and synaptic plasticity in the developing and adult nervous system. This polyclonal rabbit IgG reagent from Antibodies.com is supplied as 200 µl of unconjugated stock and is validated for western blot (WB), immunohistochemistry (IHC), and immunofluorescence (IF) workflows.

Cross-reactivity with human, mouse, and rat samples makes the antibody broadly applicable across rodent disease models and postmortem human brain tissue, supporting comparative neuroscience research. Common uses include tracking neurite extension in primary neuron cultures, monitoring phospho-regulation of MAP1B by casein kinase II and GSK3β, and probing cytoskeletal remodeling after traumatic brain injury or in neurodegenerative disease contexts. The antibody recognizes both the full-length heavy chain and the proteolytically processed light chain in lysates from cultured neurons, brain homogenates, and transfected cell lines.

Handling: Aliquot upon receipt, store refrigerated, and avoid repeated freeze-thaw cycles to preserve antigen-binding performance. For research use only.