Anti-MAGOH Antibody

Rabbit polyclonal IgG antibody targeting MAGOH, a core subunit of the exon junction complex involved in pre-mRNA splicing, mRNA export, and nonsense-mediated decay. This unconjugated reagent is supplied by Antibodies.com as 100 µl of liquid and is validated for Western blot and immunohistochemistry on human samples. The antibody recognizes endogenous MAGOH protein and is suitable for studies of spliceosome function, post-transcriptional gene regulation, and the role of MAGOH in early embryonic development and neural differentiation, where the protein's dosage is critical. Because MAGOH is haploinsufficient, even modest changes in expression can perturb downstream splicing and NMD outcomes, and a polyclonal reagent raised in rabbit helps preserve recognition across multiple epitopes of the target.