Anti-MAGED2 Antibody

This unconjugated rabbit polyclonal antibody from Antibodies.com is raised against MAGED2 (MAGE Family Member D2), a melanoma-associated antigen protein most strongly expressed in renal tissue. The IgG reagent is supplied as a 200 µl vial and is validated for Western Blot and Immunohistochemistry on human samples.

MAGED2 has attracted attention because loss-of-function mutations cause X-linked transient antenatal Bartter syndrome, and the protein acts as a chaperone-like regulator that controls the surface abundance of NKCC2 and other renal transporters. Researchers working on inherited tubulopathies, kidney development, or the broader MAGE-domain family can use this antibody to probe endogenous MAGED2 expression in cell lysates and to localize it in tissue sections. The polyclonal format offers broader epitope coverage for detection by chemiluminescence, fluorescence, or chromogenic methods.

For research use only; not intended for in vivo diagnostic or therapeutic applications.