Anti-MAGED2 Antibody

MAGED2 (MAGE Family Member D2) is a member of the melanoma antigen protein family that has drawn attention in human genetics because loss-of-function variants cause transient antenatal Bartter syndrome by impairing renal salt reabsorption through the NKCC2 transporter. This polyclonal reagent from Antibodies.com is raised in rabbit and supplied as 100 µL of unconjugated IgG, allowing direct detection of the endogenous target on Western blot and immunohistochemistry preparations of human tissue.

Investigators studying X-linked renal tubulopathies, fetal kidney development, and the broader MAGE-family interactome can use the antibody to characterise MAGED2 distribution in placenta, brain, and kidney, where it is normally enriched. Researchers typically aliquot on arrival, store frozen at -20°C in working volumes, and limit freeze-thaw cycles to preserve binding activity across the shelf life of the reagent.