Anti-MAGE-C2 Antibody

MAGE-C2 belongs to the MAGE family of cancer-testis antigens, proteins normally restricted to testicular germ cells but re-expressed in a range of human malignancies. This unconjugated rabbit polyclonal reagent from Antibodies.com targets MAGEC2 for use in Western blot and ELISA workflows with human samples, and is supplied as a 100 µL vial. Researchers studying tumor markers and candidate immunotherapy targets rely on antibodies against CT antigens to characterize antigen expression in melanoma, hepatocellular carcinoma, multiple myeloma, and other tumor types where MAGE-C2 transcripts have been detected. As a polyclonal reagent, the antibody binds multiple epitopes on the target protein, which can be helpful when probing expression patterns or when working with samples where post-translational modification may vary. The unconjugated format leaves the choice of reporter label or secondary detection system to the user, making it suitable for standard immunoblotting protocols with HRP- or fluorophore-conjugated secondaries. Researchers should validate performance in their own assay conditions and use appropriate positive and negative controls given the restricted normal-tissue expression profile of MAGE-C2.