Anti-MAFA Antibody

MAFA (MAF BZIP Transcription Factor A) is a key transcriptional regulator of insulin gene expression in pancreatic beta cells, and changes in its levels or activity are widely studied in models of type 1 and type 2 diabetes.

This rabbit polyclonal antibody from Antibodies.com is raised against human MAFA and has been validated for Western blot and immunohistochemistry on human and mouse samples, supporting both expression profiling on membranes and tissue-localization studies in fixed sections.

Supplied as 100 µl of unconjugated antiserum, the reagent lets investigators choose their own detection chemistry or label the primary reagent directly for double-labeling experiments. The polyclonal format offers recognition of multiple epitopes on the target, which is useful when probing denatured proteins or fixed tissue where a single linear epitope may be masked.

Researchers studying islet biology, glucose-stimulated insulin secretion, beta-cell maturation, or stem-cell differentiation toward an insulin-positive endocrine fate will find this reagent well matched to those workflows. Storage at -20°C in working aliquots is recommended to preserve activity across multiple freeze-thaw cycles, and brief centrifugation prior to use recovers any aggregated material that may form during long-term storage.