Anti-MAF1 Antibody

MAF1 acts as a conserved negative regulator of RNA polymerase III, repressing transcription of tRNA and 5S rRNA genes in response to nutrient availability, oxidative stress, and mTORC1 signaling. This unconjugated rabbit polyclonal antibody from Antibodies.com binds the human MAF1 target and supports Western blot and immunofluorescence workflows on cultured cells and tissue sections. The reagent ships as 100 µl of polyclonal antiserum in a single vial, allowing standard immunodetection buffers and downstream HRP- or fluorophore-conjugated secondary labeling. Polyclonal epitope coverage helps detect endogenous MAF1 across varied lysate inputs, while the unconjugated format lets researchers select their own detection chemistry. Investigators studying Pol III-dependent transcription, metabolic stress responses, and translational control use this reagent to monitor MAF1 abundance and subcellular localization in human model systems.