Anti-MACC1 Antibody

The MACC1 rabbit polyclonal reagent from Antibodies.com is an unconjugated primary antibody validated for Western blot detection of the Metastasis Associated in Colon Cancer 1 protein in human and rat samples. Supplied as a 100 µl aliquot at 1 mg/ml in phosphate buffered saline with 0.05% sodium azide at approximately pH 7.4, the antibody is ready to incorporate into standard immunoblotting workflows targeting this regulator of the HGF/MET signaling pathway.

MACC1 is a transcriptional activator linked to metastatic progression in colorectal carcinoma and several other solid tumor types, where it drives proliferation, migration, and invasion through downstream MET signaling. Investigators studying tumor metastasis, biomarker expression, or pathway activation in carcinoma models commonly use reagents like this one to assess endogenous MACC1 levels across cultured cell lines and tissue lysates. With reactivity confirmed for both human and rat, the antibody supports translational oncology studies and preclinical disease modeling that span both species.

For best results, store the vial refrigerated and protected from light to preserve activity, avoiding repeated freeze-thaw cycles that can degrade polyclonal preparations. The unconjugated format gives laboratories flexibility to pair the antibody with their own HRP, biotin, or fluorophore-conjugated secondary detection reagents depending on the Western blot imaging system in use.