Anti-LYAR Antibody

LYAR (Ly-1 antibody reactive) is a nucleolar zinc finger protein implicated in ribosome biogenesis, rRNA processing, and the maintenance of pluripotency in embryonic stem cells. The polyclonal reagent offered by Antibodies.com was raised in rabbit and affinity-purified to deliver specific detection of the LYAR target in human samples. Unconjugated IgG format preserves flexibility for downstream labelling, and the antibody is supplied in a 200 µl volume suitable for routine bench use across multiple experiments.

Validated applications include Western blot for protein-level confirmation of LYAR expression and immunohistochemistry for localisation studies in tissue sections. The reagent reacts with human LYAR, making it a useful tool for researchers studying nucleolar biology, stem cell self-renewal pathways, and emerging cancer contexts in which LYAR overexpression has been observed.

Storage at -20 °C in working aliquots helps preserve antibody activity and limit freeze-thaw cycles. Researchers should perform their own optimisation of dilution for Western blot (commonly 1:500 to 1:2000) and immunohistochemistry protocols depending on tissue preparation and detection chemistry. The polyclonal nature of the reagent provides recognition of multiple epitopes, which can improve signal robustness in variable sample types compared with monoclonal alternatives.