Anti-LYAR Antibody

Produced in rabbit and raised against the human LYAR nucleolar protein, this unconjugated polyclonal IgG reagent from Antibodies.com is supplied as 100 µl of antibody validated for western blot and immunohistochemistry on human samples. LYAR (Ly-1 antibody reactive) is a zinc-finger nucleolar factor implicated in ribosome biogenesis, rRNA maturation, and control of cell proliferation, with described roles in pluripotency programs and tumor contexts including hepatocellular carcinoma and acute myeloid leukemia. The antibody supports detection of endogenous LYAR in whole-cell lysates by western blot and visualization of nucleolar localization in formalin-fixed paraffin-embedded tissue sections by immunohistochemistry, making it useful for studies of nucleolar biology, stress responses, and oncogenic signaling. Aliquot upon receipt and store refrigerated; protect from light and minimize freeze-thaw cycles to preserve reagent activity. The polyclonal format recognizes multiple epitopes across the LYAR target, an advantage in immunohistochemistry where aldehyde fixation can mask individual epitopes.