Anti-LY86 Antibody

Specific for human LY86 (also known as MD-1), this polyclonal antibody from Antibodies.com was generated in rabbit and supplied unconjugated at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol. Each vial contains 100 µl of liquid reagent prepared for direct dilution into western blot and immunohistochemistry workflows.

LY86 functions as an accessory subunit of the RP105/MD-1 receptor complex expressed on B lymphocytes, where it supports lipopolysaccharide recognition and contributes to innate immune signaling that operates independently of classical TLR4 pathways. Tracking MD-1 expression in lymphoid tissue sections and cell lysates is a common approach in studies of B cell maturation, autoimmune disease models, and inflammatory disease mechanisms.

Aliquot the reagent upon first use and store refrigerated; protect the vial from light and limit freeze-thaw cycles to preserve antibody activity. Sodium azide serves as a preservative, so downstream live-cell staining protocols require a thorough wash step before applying the antibody to viable cells.

Antibodies.com validates each batch for application-specific performance and ships the antibody with documentation covering recommended starting dilutions, anticipated band patterns on western blot membranes, and expected staining distribution in normal and pathological lymphoid specimens.