Anti-LY75 Antibody

Raised in rabbits against the LY75 antigen, this unconjugated polyclonal IgG preparation from Antibodies.com is supplied at 50 µl working volume and is validated for Western blot workflows. LY75, also termed CD205 or DEC-205, is a multi-lectin endocytic receptor that decorates cortical thymic epithelium and most dendritic cell subsets, where it mediates capture of antigens for processing onto MHC class II and presentation to T cells. Cross-reactivity data confirm recognition of human, mouse, and rat LY75 orthologs, supporting translational studies that compare receptor expression across species.

Typical downstream uses include dendritic-cell trafficking experiments, vaccine targeting research, and immunological phenotyping of lymphoid tissues. The vial should be stored at -20 °C, with working aliquots kept separate to limit freeze-thaw cycles, and protected from light to preserve IgG activity. Investigators studying antigen routing to lymphoid organs, cancer vaccine strategies, or thymic selection models will find this polyclonal reagent useful as a detection layer in lysate-based Western blot readouts.