Anti-LY75 Antibody

This rabbit polyclonal reagent targets LY75, the multi-lectin endocytic receptor commonly referenced as DEC-205 or CD205. Antibodies.com supplies the antibody as an unconjugated IgG preparation in a 200 µL vial, validated for Western blot detection of the target in human, mouse, and rat samples. LY75 is predominantly expressed on dendritic cell populations and related antigen-presenting lineages, where it mediates capture and intracellular routing of antigens for processing in MHC class II compartments. Laboratories investigating immune cell biology, vaccine delivery platforms, and tumor microenvironment immunology use anti-LY75 reagents to confirm dendritic subset presence and to study receptor-mediated antigen uptake pathways. As a polyclonal reagent, the antibody recognizes multiple epitopes on the LY75 protein, which is useful when working with denatured lysates or when epitope diversity is required across different experimental conditions. The unconjugated format allows pairing with HRP, fluorescent, or biotin-based secondary detection systems, supporting flexibility in membrane-based detection workflows. For research use only; store refrigerated and avoid repeated freeze-thaw cycles to preserve binding activity.