Anti-Ly6a Antibody

Ly6a, the mouse Lymphocyte antigen 6 complex locus A glycoprotein better known as Sca-1, is widely used as a surface marker for hematopoietic stem and progenitor cells, and this rabbit polyclonal reagent from Antibodies.com offers a flexible unconjugated format for detecting the protein in both Western blot and immunohistochemistry workflows.

Supplied as a 100 µl liquid aliquot, the antibody is raised in rabbit and affinity-purified from polyclonal sera, with reactivity validated specifically against mouse Ly6a. The unconjugated presentation allows pairing with a laboratory's preferred secondary antibody, chromogen, or fluorophore rather than restricting users to a pre-labeled kit. Researchers commonly apply anti-Ly6a to track hematopoietic stem cell enrichment, characterize mesenchymal progenitor populations, and probe Sca-1 expression in tumor and tissue sections.

The reagent performs in Western blot for band detection around the expected Ly6a molecular weight and in immunohistochemistry on fixed tissue sections. Aliquot upon first use and store refrigerated to limit freeze-thaw cycles; protect the vial from light to preserve reagent integrity across the shelf life of the stock.