Anti-LUM Antibody

Raised in rabbit against the human lumican (LUM) protein, this unconjugated polyclonal antibody from Antibodies.com is supplied as 100 µl of reagent validated for western blot (WB) and immunohistochemistry (IHC) workflows on human samples. Lumican is a small leucine-rich keratan sulfate proteoglycan of the extracellular matrix, best characterized for its role in organizing collagen fibril architecture in the cornea, skin, tendon, and interstitial connective tissues. Researchers apply anti-LUM reagents to studies of corneal transparency, dermal and tendon wound healing, fibrotic remodeling, stromal contributions to tumor biology, and age-related changes in connective tissue composition. The unconjugated format lets laboratories pair the primary reagent with their preferred secondary detection system, including HRP, fluorescent, or biotin-streptavidin reporters, supporting both chromogenic IHC on fixed tissue sections and standard immunoblotting of cell or tissue lysates. Host species (rabbit) and polyclonal clonality provide broad recognition across the lumican core protein, an important consideration when probing proteoglycan-rich matrices where epitope accessibility can vary with tissue-specific glycosylation.