Anti-LTF Antibody [Assigned #A1597]

The unconjugated mouse monoclonal reagent from Antibodies.com targets lactoferrin (LTF), an iron-binding glycoprotein secreted by mucosal epithelial cells and released from neutrophil secondary granules during inflammation. The antibody is supplied as 100 µl of mouse IgG and is validated for Western blot, immunohistochemistry, and immunofluorescence workflows across human, mouse, and rat samples.

Lactoferrin contributes to innate mucosal defense through bacterial iron sequestration, direct interactions with microbial membranes, and modulation of host inflammatory pathways. Researchers commonly deploy LTF antibodies to study epithelial barrier function in mammary, respiratory, and gastrointestinal tissues, and to track neutrophil activation in tissue injury and infection models. The unconjugated format allows flexible selection of secondary detection reagents, including tyramide signal amplification, biotinylation, and fluorophore conjugation in flow cytometry and imaging panels.

Working dilution varies by application, but the antibody typically performs well on formalin-fixed paraffin-embedded sections and standard RIPA lysates. Refrigerate the vial upon arrival and avoid repeated freeze-thaw cycles to preserve binding activity; aliquot for long-term projects requiring consistent lot performance.