Anti-LTBR Antibody

This rabbit polyclonal antibody specifically recognizes human Lymphotoxin-beta receptor (LTBR), also known as TNFRSF3 or CD18, a member of the tumor necrosis factor receptor superfamily that mediates NF-kappaB activation and supports lymphoid tissue organogenesis and inflammatory signaling. Produced and validated by Antibodies.com, the reagent is supplied as 100 µl of unconjugated antisera raised in rabbit and is intended for research use only. It has been validated in Western blot and immunohistochemistry workflows against human samples, supporting studies of stromal-epithelial crosstalk in secondary lymphoid organs, host defense, and tumor microenvironment biology. The polyclonal format provides broader epitope coverage than monoclonal alternatives, which is useful when probing conformational or post-translationally modified variants of the receptor. Aliquot the antibody upon receipt and keep it refrigerated to preserve binding activity; limiting freeze-thaw cycles is also recommended. For detection in immunohistochemistry, antigen retrieval conditions should be optimized empirically, and pairing with an HRP- or fluorescent-labeled secondary reagent matched to the rabbit host yields clean signal in formalin-fixed paraffin-embedded tissue sections.