Anti-LSP1 Antibody

Polyclonal antibody raised in rabbit against Lymphocyte-Specific Protein 1 (LSP1), an intracellular F-actin binding protein expressed predominantly in hematopoietic cells, including B and T lymphocytes, neutrophils, and monocytes. LSP1 functions as a substrate for MAPKAP kinase 2 and related serine/threonine kinases downstream of integrin and chemokine signaling, and it contributes to leukocyte adhesion, chemotaxis, and transendothelial migration during innate and adaptive immune responses. This unconjugated reagent from Antibodies.com is supplied as a 50 µL aliquot and has been validated for Western blot and immunohistochemistry applications. The antibody recognizes mouse, rat, and human LSP1, supporting comparative studies across species in immunology, hematology, and inflammation research. Practical uses include detection of endogenous LSP1 in lymphoid tissues, profiling of leukocyte activation states, and analysis of cytoskeletal remodeling that accompanies immune cell migration.