Anti-LRRTM1 Antibody

This unconjugated polyclonal IgG antibody offered by Antibodies.com targets LRRTM1, a leucine-rich repeat transmembrane neuronal protein that localizes to excitatory postsynaptic sites and binds presynaptic neurexins to promote synapse organization and differentiation. Raised in rabbit and supplied as 100 µl of antiserum, it is suited to western blot and immunohistochemistry workflows.

The reagent detects human and mouse LRRTM1 and is widely used in neuroscience research investigating glutamatergic synapse development, post-synaptic density protein interactions, and the wiring of cortical circuits. Published studies have linked LRRTM1 to handedness, language lateralization, and susceptibility loci associated with schizophrenia and other neurodevelopmental disorders, making it a useful reagent for studies probing these mechanisms at the molecular and circuit level.

Shipped as a liquid aliquot in a single vial, the antibody can be stored under standard short-term refrigeration conditions and aliquoted to limit freeze-thaw cycles of the working stock. The unconjugated format allows laboratories to pair it with their preferred secondary detection reagents for chromogenic or fluorescence-based IHC, or for chemiluminescent western blot imaging of LRRTM1 expression in tissue lysates and brain sections.