Anti-LRPAP1 Antibody

LRPAP1 (LDL receptor-related protein-associated protein 1) functions as a molecular chaperone within the endoplasmic reticulum, assisting the proper folding and intracellular trafficking of members of the low-density lipoprotein receptor family. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against human LRPAP1 and is validated for Western blot and immunohistochemistry workflows, supporting detection of the endogenous protein in cell lysates and in formalin-fixed tissue sections respectively.

Provided as 100 µl of polyclonal antiserum in a vial format, the antibody binds the LRPAP1 target without enzymatic or fluorescent labeling, making it compatible with a wide choice of secondary detection reagents and chromogenic substrates chosen by the end user. Researchers studying lipoprotein metabolism, receptor-mediated endocytosis, and neurodegenerative disease models linked to amyloid precursor protein processing use LRPAP1 antibodies to map chaperone distribution, monitor receptor trafficking dynamics, and interrogate interactions between LRPAP1 and LDL receptor family members such as LRP1, LRP2, and VLDL receptor.

Because the reagent is supplied as a research-use-only polyclonal reagent in liquid form, aliquoting upon first use is recommended to limit freeze-thaw cycles and preserve titer across repeated experiments. The unconjugated format gives laboratories flexibility to pair the antibody with HRP-, biotin-, or fluorophore-conjugated secondaries suited to their preferred detection platform.