Anti-LRP4 Antibody

LRP4 (Low-density lipoprotein receptor-related protein 4) is a single-pass transmembrane receptor central to Wnt signaling, bone homeostasis, and the assembly of the neuromuscular junction. This rabbit polyclonal IgG antibody targets LRP4 and is supplied by Antibodies.com as an unconjugated preparation in a 50 µL vial, validated for western blot analysis of human and mouse samples.

The reagent is suited to studies of osteoblast differentiation, skeletal disorders such as osteoporosis and Cenani-Lenz syndrome, agrin-dependent MuSK signaling at the motor endplate, and autoimmune myasthenia gravis where anti-LRP4 autoantibodies have been documented in patient sera. Polyclonal reactivity supports recognition of multiple epitopes on the target protein, and the IgG isotype is broadly compatible with standard HRP, alkaline phosphatase, or fluorescent secondary antibodies for downstream immunodetection workflows.