Anti-LPXN Antibody

Raised in rabbit against human leupaxin, this unconjugated polyclonal IgG reagent from Antibodies.com detects the paxillin-family scaffolding protein LPXN across human, mouse, and rat samples. The 100 µl volume is supplied as a liquid antiserum validated for Western blot, where it recognizes the endogenous target that localizes to focal adhesions and podosomes in hematopoietic cells.

LPXN participates in cytoskeletal remodeling through its LD and LIM domains, recruiting partners such as focal adhesion kinase during leukocyte migration and integrin-based adhesion signaling. Researchers tracking phosphorylation of LPXN or its binding partners in prostate cancer cell invasion, osteoclast adhesion, or lymphocyte activation rely on this reagent to resolve the protein on immunoblots of whole-cell lysates. Aliquot upon receipt and store refrigerated; avoid repeated freeze-thaw cycles to preserve antibody activity across multiple experiments.