Anti-LPAR1 Antibody

Raised in rabbit, this unconjugated polyclonal IgG reagent from Antibodies.com targets the human Lysophosphatidic Acid Receptor 1 (LPAR1), a G protein-coupled receptor that binds extracellular lysophosphatidic acid. Supplied as 100 µl of polyclonal antiserum and validated for Western Blot, the antibody detects LPAR1 in human cell lysates and tissue samples. LPAR1 is widely expressed across tissues and has been studied in the context of Schwann cell biology, myelination, fibroblast activation, vascular signaling, and tumor cell migration, making it a relevant target for neuroscience, fibrosis, and oncology research programs. As a polyclonal reagent, the antibody recognizes multiple epitopes on the receptor, which is useful when probing samples that may contain receptor splice variants or post-translationally modified forms. Standard handling for this format includes refrigerated storage for active use and aliquoting for longer-term storage at -20 °C to limit freeze-thaw damage to the IgG. The unconjugated format allows investigators to choose their own secondary detection system, such as HRP-conjugated anti-rabbit IgG for chemiluminescent Western Blot or fluorescent secondaries for multiplex imaging. For lysates from human cell lines, primary tissue, and membrane-enriched fractions, this reagent offers a flexible option for surveying LPAR1 expression alongside signaling and functional studies of the lysophospholipid pathway.