Anti-LMNB2 Antibody

Lamin B2 (LMNB2) is a type V intermediate filament protein that contributes to the structural scaffold of the nuclear envelope and helps maintain chromatin organization at the nuclear periphery. The Antibodies.com Anti-LMNB2 Antibody is a rabbit polyclonal reagent raised against human Lamin B2, supplied as 100 µl of unconjugated antibody. Recommended applications include Western blot (WB) and immunofluorescence (IF) on human samples, where the antibody produces perinuclear and rim staining patterns consistent with nuclear lamina localization. In Western blot, a discrete band near the predicted molecular weight of Lamin B2 is typically observed. As a polyclonal reagent raised in rabbit, the antibody recognizes multiple epitopes, which can improve signal robustness in varied experimental conditions. Researchers studying nuclear architecture, cellular senescence, differentiation pathways, or programmed cell death can use this antibody to investigate changes in LMNB2 expression or distribution. For optimal stability, the antibody should be stored refrigerated and protected from repeated freeze-thaw cycles to preserve binding activity over time.