Anti-LITAF Antibody

This rabbit polyclonal primary antibody targets LITAF (Lipopolysaccharide-Induced Transcription Factor), a small transcription regulator originally identified through its rapid induction by bacterial lipopolysaccharide in macrophages. The unconjugated reagent is supplied by Antibodies.com at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, a cryoprotective formulation that supports storage at -20 °C in working aliquots to limit freeze-thaw cycles of the stock vial. Validated applications include Western blot, immunohistochemistry, and immunofluorescence, with cross-reactivity confirmed for human, mouse, and rat samples, making the reagent suitable for comparative studies across rodent disease models and human tissue. The 100 µl pack size provides enough volume for multiple staining and blotting experiments in cell culture and fixed-tissue workflows. Because LITAF governs cytokine output (including TNF-alpha release) and contributes to lysosomal protein trafficking, researchers working on innate immunity, macrophage signaling under inflammatory stimuli, and Charcot-Marie-Tooth disease type 1C (CMT1C) mutation biology rely on this antibody to map protein expression, monitor induction kinetics, and resolve subcellular localization by immunofluorescence staining.