Anti-Liprin alpha 1 Antibody

This rabbit polyclonal primary antibody targets Liprin alpha 1 (PPFIA1), a multi-domain scaffolding protein that localises to presynaptic active zones and recruits LAR-family receptor tyrosine phosphatases. Liprin alpha 1 orchestrates synaptic vesicle trafficking, neurotransmitter release, and the assembly of cytoskeletal scaffolds at excitatory synapses, and it is also implicated in cell adhesion, focal adhesion turnover, and integrin signalling outside the nervous system.

Produced in rabbit and supplied as an unconjugated reagent in a 100 µl vial, the antibody is validated for Western blot and immunofluorescence applications on human samples and is intended for research use only. Researchers commonly use it to probe endogenous PPFIA1 distribution in neuronal cultures, brain tissue sections, and cell lines, and it has been referenced in studies of synaptic organiser biology and active-zone proteomics. For best results, store the vial refrigerated, avoid repeated freeze-thaw cycles, and aliquot on first use to preserve polyclonal reactivity.

Reactivity is reported for human, and the polyclonal format increases the likelihood of recognising multiple epitopes across isoforms of the target. For full validation data, species reactivity panels, and supporting references, contact Antibodies.com.