Anti-LIPC Antibody

Hepatic lipase (LIPC) is a key enzyme in lipid metabolism that catalyzes the hydrolysis of triglycerides and phospholipids in circulating lipoproteins, including HDL and LDL particles. This Rabbit polyclonal antibody from Antibodies.com was raised against human LIPC and is validated for Western blot, immunohistochemistry, and immunofluorescence workflows. Supplied as 100 µl of unconjugated antisera, the reagent leaves labeling strategy open, so it can be paired with a secondary reagent chosen for the chromogen, fluorophore, or enzyme reporter a given protocol requires. Hepatic lipase is synthesized primarily by hepatocytes and acts at the hepatic sinusoidal surface, where it remodels the lipid core of lipoproteins and helps set plasma HDL-cholesterol concentrations. Researchers use LIPC antibodies to probe hepatic lipid handling, follow up on coding and non-coding variants linked to dyslipidemia and atherosclerotic cardiovascular risk, and visualize expression in liver tissue sections or cultured hepatocyte models. For best results, store aliquots at -20 °C and limit freeze-thaw cycles so activity is retained across multiple experiments.