Anti-LIMK1 Antibody [Assigned #A0547]

This mouse monoclonal primary antibody targets LIMK1, a serine/threonine kinase that phosphorylates cofilin to regulate actin filament turnover and cytoskeletal remodeling. Produced and qualified by Antibodies.com, the IgG clone is supplied as 200 µl of unconjugated sample in a single-use vial and is validated for Western blot workflows against endogenous LIMK1 from human and mouse lysates.

Because LIMK1 controls cofilin activity at the leading edge of migrating cells and at synaptic contacts, this reagent has been applied to studies of neurite outgrowth, neuronal cytoskeletal organization, and actin-driven cell motility research. Researchers investigating Williams-Beuren syndrome-associated pathways, where LIMK1 haploinsufficiency contributes to neurological and cognitive features, also use this clone as a detection reagent for protein-level analysis of the kinase in disease models.

The unconjugated format allows flexible pairing with secondary antibodies of choice across imaging and immunoblotting platforms. Store refrigerated and avoid repeated freeze-thaw cycles to preserve activity across the shelf life of the reagent.