Anti-Lgi4 Antibody [KT18]

The Anti-Lgi4 Antibody [KT18] from Antibodies.com is a rat monoclonal IgG1 reagent raised against mouse leucine-rich glioma-inactivated 4 (Lgi4), a secreted leucine-rich repeat protein best known for its essential role in Schwann cell differentiation and peripheral nerve myelination. Supplied as 100 µg of liquid in a single vial, this unconjugated primary antibody is validated for western blot and immunofluorescence workflows and binds the native Lgi4 protein in mouse tissue preparations, including teased peripheral nerve fibers and cultured Schwann cells. The KT18 clone has been referenced in published studies investigating axon-glia signaling, node of Ranvier organization, and the regulation of myelin thickness, making it a useful reagent for neuroscience and neurodevelopmental research programs that examine how Lgi4 mutations disrupt nerve development in mouse models. For best results, store aliquots at -20 °C, avoid repeated freeze-thaw cycles, and protect from light until use. This antibody is intended for research use only.