Anti-LFNG Antibody

Rabbit polyclonal IgG antibody raised against LFNG (Lunatic Fringe Glucosaminyltransferase), a Golgi-resident glycosyltransferase that modulates Notch signaling by transferring N-acetylglucosamine onto O-fucose residues on the EGF-like repeats of Notch receptors. This unconjugated reagent from Antibodies.com is supplied as 100 µl of polyclonal rabbit serum and is validated for western blot and immunohistochemistry on human, mouse, and rat samples. Researchers commonly apply it to study somite segmentation during embryogenesis, T-cell lineage commitment at the β-selection checkpoint in the thymus, and disease states linked to disrupted Notch pathway activity, including spondylocostal dysostosis and certain malignancies in which Notch-driven proliferation is dysregulated.

Key specifications: host Rabbit; clonality Polyclonal; isotype IgG; conjugate Unconjugated; target LFNG; reactivity Human, Mouse, Rat; applications Western Blot (WB) and Immunohistochemistry (IHC); format 100 µl vial.