Anti-Lfc Antibody

This rabbit polyclonal antibody from Antibodies.com targets Lfc, the murine and rat orthologue of ARHGEF2, a Dbl-family Rho guanine nucleotide exchange factor that couples upstream signals to RhoA activation. The reagent is supplied as an unconjugated polyclonal antiserum in a 100 µl volume and is validated for western blot and ELISA workflows against human, mouse, and rat samples, supporting studies of cytoskeletal remodelling, focal adhesion turnover, mitotic spindle assembly, and Rho-mediated signalling in cell migration and division.

Affinity-purified from rabbit serum, the antibody enables detection of endogenous Lfc in lysates prepared from cultured mammalian cells and primary tissues. Researchers investigating Rho GTPase biology, neuronal development, and cancer cell invasion use the reagent to probe Lfc phosphorylation, membrane translocation, and binding partner interactions. The unconjugated format allows flexible pairing with HRP, fluorescent, or biotin secondary reporters depending on the assay design. For best results, aliquot on receipt and limit freeze-thaw cycles to preserve antibody activity across repeated experiments.