Anti-LETM1 Antibody

LETM1 (Leucine zipper-EF-hand containing transmembrane protein 1) is a mitochondrial inner membrane protein that functions as a Ca2+/H+ antiporter, playing central roles in mitochondrial ion homeostasis and volume regulation. This unconjugated rabbit polyclonal antibody from Antibodies.com is raised against LETM1 and validated for western blot, immunohistochemistry, and immunofluorescence workflows on human samples. The reagent is supplied as a 100 ul liquid aliquot of polyclonal serum, suitable for detection of the endogenous LETM1 protein in cell and tissue lysates. Because LETM1 resides in the inner mitochondrial membrane, the antibody is commonly used to study mitochondrial calcium handling, bioenergetics, and the contribution of LETM1 loss or overexpression to disease models including Wolf-Hirschhorn syndrome and various cancers where mitochondrial homeostasis is disrupted.

Host: Rabbit. Clonality: Polyclonal. Conjugate: Unconjugated. Reactivity: Human. Target: LETM1. Applications: WB, IHC, IF.