Anti-LDHA Antibody [L46-2]

The Antibodies.com anti-LDHA monoclonal antibody (clone L46-2) specifically recognizes lactate dehydrogenase A, a 37 kDa cytosolic enzyme that catalyzes the interconversion of pyruvate and L-lactate during anaerobic glycolysis. This unconjugated mouse IgG1 reagent is validated for western blot analysis of protein expression and immunohistochemistry on paraffin-embedded tissue sections, supporting studies of tumor metabolism, the Warburg effect, and hypoxia signaling in human and mouse samples.

Supplied as 100 µg in liquid format, the antibody should be stored at -20 °C in single-use aliquots to preserve activity through repeated freeze-thaw cycles. Researchers commonly use this clone to investigate LDHA upregulation in cancer cell lines and to compare isoform-specific expression patterns between glycolytic and oxidative tissues.