Anti-LDHA Antibody

Produced in rabbit and supplied as 100 µl of unconjugated antiserum, this polyclonal primary antibody from Antibodies.com targets Lactate Dehydrogenase A (LDHA), the muscle-type M subunit of the LDH tetramer that converts pyruvate to L-lactate while regenerating NAD+ during anaerobic glycolysis. The reagent is validated for Western blot and immunohistochemistry on human, mouse, and rat samples, supporting experiments in cancer metabolism, the Warburg effect, and hypoxia signaling where LDHA expression and post-translational regulation are routinely interrogated. As a polyclonal reagent, the antibody recognizes multiple epitopes across the LDHA monomer, allowing flexibility in detecting both full-length protein and processed or truncated forms under denaturing or native conditions. The unconjugated format leaves open the choice of secondary detection chemistry, from HRP and alkaline phosphatase to fluorescent dyes, so the same vial can be carried across WB, IHC, and related assay platforms. For storage and handling, the supplier recommends refrigerated short-term keeping with aliquoting and freezing for longer term use to preserve activity across repeated freeze-thaw cycles.