Anti-LDB3 Antibody

Rabbit polyclonal antibodies directed against LDB3 (also known as ZASP or Cypher) offer a reagent for studying this sarcomeric protein central to cardiac and skeletal muscle architecture. Produced in rabbit and supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a stabilizer, this unconjugated antibody from Antibodies.com is validated for Western blot and immunohistochemistry workflows. Cross-reactivity with human, mouse, and rat LDB3 supports translational studies of dilated cardiomyopathy, left ventricular non-compaction, and myofibrillar myopathy, conditions linked to mutations in the ZASP/LDB3 gene. Each vial contains 100 µl of polyclonal reagent, prepared to minimize freeze-thaw handling, and the polyclonal format enables detection of full-length LDB3 alongside its tissue-specific isoforms expressed in striated muscle. Storage at -20 °C preserves antibody activity for repeated experimental use in studies of sarcomere assembly and Z-disc signaling.