Anti-LCAT Antibody

Polyclonal antibody raised in rabbit against human lecithin-cholesterol acyltransferase (LCAT), an enzyme that catalyzes esterification of cholesterol within nascent HDL particles and is central to reverse cholesterol transport. Produced as an unconjugated IgG preparation supplied at 100 µl, this reagent is validated for Western blot detection across human, mouse, and rat samples, and performs reliably in immunohistochemistry on fixed tissue sections where it localizes LCAT signal to hepatocytes and renal tubular epithelium.

The antibody recognizes epitopes conserved across species, supporting studies of HDL biogenesis, atherosclerosis models, and rare disorders linked to LCAT loss of function such as familial LCAT deficiency and fish-eye disease. From Antibodies.com, it is packaged as a liquid aliquot appropriate for both reducing and non-reducing SDS-PAGE workflows, and the polyclonal response helps preserve immunoreactivity when individual epitopes are masked by sample preparation.