Anti-LAYN Antibody

LAYN (Layilin) is a 55 kDa transmembrane receptor that binds hyaluronic acid and modulates cytoskeletal dynamics through interactions with the ERM (ezrin-radixin-moesin) family of proteins. Antibodies.com offers this rabbit polyclonal IgG reagent for Western blot detection of Layilin in human and murine samples, supporting research into cell adhesion, immune signaling, and the tumor microenvironment.

The unconjugated format allows flexibility for downstream labeling with HRP, fluorophores, or biotin depending on the detection chemistry required. As a polyclonal reagent, the antibody recognizes multiple epitopes across the target protein, which can be advantageous when probing for isoforms or partially degraded samples in lysate preparations. Researchers investigating tumor-infiltrating regulatory T cells, where LAYN has been identified as a marker of suppressive CD4+ T cell subsets in certain cancer types, use this reagent to profile expression by Western blot.

Validated reactivity across human and mouse species makes the antibody suitable for translational studies comparing Layilin expression between model systems and clinical samples. Each vial contains 100 µL of antibody, and the reagent should be handled according to standard immunological protocols for primary antibodies.