Anti-LASP-1 Antibody

Raised in rabbit against the LIM and SH3 protein 1 (LASP-1) target, this polyclonal primary antibody from Antibodies.com is supplied as an unconjugated, ready-to-use reagent in a 100 µL volume. LASP-1 is a focal adhesion and actin-cytoskeleton-associated phosphoprotein of roughly 38-40 kDa that participates in integrin signaling, cell migration, and cytoskeletal remodeling, and it has been most extensively studied in the context of tumor cell motility and metastatic behavior across multiple carcinoma models.

Validated for western blot and ELISA applications, this reagent recognizes the human LASP-1 sequence and shows cross-reactivity with mouse and rat orthologs. It supports immunoblotting of focal adhesion and cytoskeletal fractions, characterization of LASP-1 phosphorylation and subcellular redistribution, and ELISA-based quantitation in cell lysate or tissue extract samples.

For best results, aliquot upon first thaw to limit freeze-thaw cycles, store refrigerated for short-term use, and protect from light. Researchers should note that LASP-1 migrates as a single dominant band in standard reducing SDS-PAGE conditions.