Anti-LARGE Antibody

Rabbit polyclonal antibody targeting LARGE1, a glycosyltransferase essential for proper dystroglycan glycosylation. Researchers apply this reagent from Antibodies.com to investigate dystroglycanopathies, including congenital muscular dystrophy variants caused by impaired dystrophin-glycoprotein complex assembly. The unconjugated IgG is supplied as 100 µl in a vial ready for western blot workflows probing human cell and tissue lysates. For long-term integrity, store at -20 degrees C and avoid repeated freeze-thaw cycles by aliquoting on first use. This polyclonal reagent enables detection of endogenous LARGE expression across human samples, supporting studies of arenavirus receptor biology and dystroglycanopathy mechanisms. Each preparation is affinity-validated for standard immunoblotting applications in research use only.